Beta 1 -Adrenergic Receptor Regulation Revisited
نویسندگان
چکیده
منابع مشابه
Beta-2 adrenergic receptor
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via a downstream Ltype calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation. Unlike other adr...
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Address reprint requests to Dr. Galant, Memorial Hospital Medical Center of Long Beach, Calif. Received for publication 12 August 1980 and in revised form 23 March 1981. group to include agonist binding, receptor-adenylate cyclase coupling, intrinsic adenylate cyclase activity, and catecholamine metabolism may help determine the basic cause of beta adrenergic hyporesponsiveness in both CFH and CF.
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The beta(1)-adrenergic receptor (beta(1)AR) is the most abundant subtype of beta-adrenergic receptor in the mammalian brain and is known to potently regulate synaptic plasticity. To search for potential neuronal beta(1)AR-interacting proteins, we screened a rat brain cDNA library using the beta(1)AR carboxyl terminus (beta(1)AR-CT) as bait in the yeast two-hybrid system. These screens identifie...
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Mammalian pineal function is regulated by norepinephrine acting through alpha1beta- and beta1-adrenergic receptors (ARs). Noradrenergic stimulation of alpha1beta-ARs potentiates the beta1-AR-driven increase in cAMP, serotonin N-acetyltransferase, and melatonin production. In the present study, we describe a 3-fold daily rhythm in mRNA-encoding alpha1beta-ARs in the pineal gland, with a peak at ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2018
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.118.313884